Episode 17: Gabapentin Abuse

On today’s Medication Minute, we will be discussing gabapentin, including its pharmacology, use in management of psychiatric diagnoses, and it’s more recent growing potential for abuse. Gabapentin is a gamma-aminobutyric acid analog that is was approved for use as an antiepileptic in 1993 and for post-herpetic neuralgia in 2004, but is also used off label for alcohol withdrawal symptoms, diabetic neuropathy, fibromyalgia, restless legs syndrome, and other types of neuropathic pain.


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  3. Reccoppa, Lawrence, et al. “Gabapentin abuse in inmates with prior history of cocaine dependence.” American Journal on Addictions, vol. 13, no. 3, 2004, pp. 321-323., doi:10.1080/10550490490460300.
  4. “Gabapentin: Drug information.” com. Web. 18 October 2018.
  5. Peckham, Alyssa M. et al. “Prevalence of gabapentin abuse: comparison with agents with known abuse potential in a commercially insured US population.” Clinical Drug Investigation, 37, no. 8, 2018, pp. 763-773., doi:10/1007/s40261-017-0530-3. 20 October 2018.
  6. Berlin, Rachel K., et al. “Gabapentin Therapy in Psychiatric Disorders.” The Primary Care Companion For CNS Disorders, 2015, doi:10.4088/pcc.15r01821. 24 October 2018.